NG2 and GFAP co-expression after differentiation in cells transfected with mutant GFAP and in undifferentiated glioma cells
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چکیده
منابع مشابه
Expression of Endoderm and Hepatic Specific Genes after in vitro Differentiation of Human Embryonic Stem Cells
Background: Human embryonic stem cells (hESC), which are derived from the inner cell mass of the blastocysts, have been considered to be pluripotent cells. In this study we examine the differentiating potential of hESC into hepatocytes by characterization of the expression of endoderm and liver-specific genes. Methods: hESC were cultivated in suspension to form aggregates, the embryoid bodies. ...
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BACKGROUND Naringenin, a flavanone, has been reported to exhibit a wide range of pharmacological properties including antitumor activity. PURPOSE We wanted to test the efficacy of Naringenin on C6 glioma cells-implanted into rats was investigated. METHODS Biochemical and immunohistochemical methods were used for analyzing various markers. RESULTS Injection of C6 glioma cells into rat brai...
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Glial fibrillary acidic protein (GFAP) is one of the best markers for the activation of astrocytes (AS) following injury or stress in the central nervous system (CNS). The purpose of this study was to examine the expression of GFAP and 14-3-3ε in rat AS subjected to hypoxia. We established primary cultures of AS from cerebral cortex of neonatal Sprague-Dawley rats as a model of glucose deficien...
متن کاملAbnormal reactivity of muller cells after retinal detachment in mice deficient in GFAP and vimentin.
PURPOSE To determine the roles of glial fibrillary acidic protein (GFAP) and vimentin in Müller cell reactivity. METHODS Retinal detachments were created in mice deficient for GFAP and vimentin (GFAP(-/-)vim(-/-)) and age-matched wild-type (wt) mice. The reactivity of the retina was studied by immunofluorescence and electron microscopy. RESULTS Müller cell morphology was different and gluta...
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ژورنال
عنوان ژورنال: Neurología (English Edition)
سال: 2020
ISSN: 2173-5808
DOI: 10.1016/j.nrleng.2017.11.001